Benadryl Side Effects

Benadryl Side Effects - Product

Benadryl Side Effects - Benadryl's drug class and mechanism - Diphenhydramine Benadryl is an antihistamine with drying and sedative effects. It relieves red, inflamed eyes caused by food allergies and the itching, swelling, and redness from hives and other rashes that are caused by mild allergic reactions. It also relieves the sneezing, coughing, runny or stuffy nose, and red, teary, itching eyes caused by seasonal allergies and the common cold. Antihistamines work by decreasing the effects of histamine, a chemical released in the body that narrows air passages in the lungs and contributes to inflammation. Antihistamines reduce itching and swelling and dry up secretions from the nose, eyes, and throat.


PRESCRIBED FOR: Diphenhydramine is used for the relief of nasal and non-nasal symptoms of various allergic conditions such as seasonal allergic rhinitis. It is also used to alleviate cold symptoms and hives.

Benadryl Side Effects

Diphenhydramine (Benadryl) can commonly cause:

  • sedation

  • tiredness

  • sleepiness

  • dizziness

  • disturbed coordination

  • drying and thickening of oral and other respiratory secretions

  • and stomach distress

Benadryl Additional Side Effects

Diphenhydramine (Benadryl) may also cause:
  • low blood pressure

  • palpitations

  • increased heart rate

  • confusion

  • nervousness

  • irritability

  • blurred vision

  • double vision

  • tremor

  • or nausea

Benadryl Side Effects - Use with Caution

Diphenhydramine (Benadryl) - should be used with caution (if at all) in persons with narrow-angle glaucoma, enlarged prostate gland, hyperthyroidism, cardiovascular disease, hypertension, and asthma.

PREGNANCY: Diphenhydramine (Benadryl) has not been adequately evaluated in pregnant women. It should be used only if the benefit outweighs the potential but unknown risks.

NURSING MOTHERS: Diphenhydramine (Benadryl) is secreted in breast milk. Because of the risk of stimulation and seizures in infants, especially newborns and premature infants, antihistamines should not be used by nursing mothers.

Benadryl Side EffectsPossible food and drug interactions when taking this medication.

Benadryl may increase the effects of alcohol, and alcohol may increase the sedative effects of Benadryl. Do not drink alcohol while taking this medication.

If Benadryl is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Benadryl with the following:
  • Antidepressant drugs known as MAO inhibitors, such as Parnate and Nardil

  • Sedative/hypnotics such as Halcion, Nembutal, and Seconal Tranquilizers such as Xanax and Valium

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